Author

Sonika Rathi

University of PennsylvaniaORCID 0000-0003-0484-9952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:rat· 1

Frequent Co-Authors

Jie HeiD· 2 shared Joan M. O’BrieniD· 2 shared Venkata Ramana Murthy ChavaliiD· 2 shared Ahmara G. RossiD· 1 shared Amanda Y. Lehman· 1 shared Anastasia Lucas· 1 shared Anita S. BowmaniD· 1 shared Athanasios DidangelosiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Jie HeORCID

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3 papers

Recent·Most cited

BiochemistryOphthalmology SciencePeer-reviewedOct 22, 2025

CTx001 for geographic atrophy: a gene therapy expressing soluble, truncated complement receptor 1 (mini-CR1)

Sonika Rathi, Athanasios Didangelos, Sofiya Pisarenka…·Simon J. Clark

This paper develops CTx001, a gene therapy expressing mini-CR1, which reduces MAC formation in a rat model of geographic atrophy.

3 citations

ratexperimental assay

NeuroscienceScientific ReportsPeer-reviewedJul 16, 2020

Dual SMAD inhibition and Wnt inhibition enhances the differentiation of induced pluripotent stem cells into Retinal Ganglion cells (iPSC-RGCs)

Venkata Ramana Murthy Chavali, Naqi Haider, Sonika Rathi…·Jason A. Mills

This study develops a reproducible method to differentiate iPSCs into RGCs with high purity using dual SMAD and Wnt pathway inhibition.

46 citations

humanbulk RNA-seq

GeneticsbioRxivPreprintFeb 27, 2020

Genome wide-association study identifies novel loci in the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study

Harini V. Gudiseva, Shefali S. Verma, Venkata Ramana Murthy Chavali…·Joan M. O’Brien

The paper identifies a novel POAG-associated SNP in African Americans using a genome-wide association study.

13 citations

humanGWAS summary statistics