Mitochondrial DNA metabolism is coupled with 20S proteasome function via regulation of deoxyribonucleotide homeostasis in Saccharomyces cerevisiae
Xiaowen Wang, Arnav Rana, Liam P. Coyne, Daniel M. Loh, Thuy La, Xin Jie Chen
The paper shows that 20S proteasome function regulates mtDNA stability in yeast by controlling dNTP homeostasis through Sml1 degradation.
bioRxiv · Nov 30, 2021 · PreprintGenetics