Author

Liam P. Coyne

SUNY Upstate Medical UniversityORCID 0000-0002-4480-126XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

Arnav Rana· 2 shared Xin Jie CheniD· 2 shared Daniel M. LohiD· 1 shared Eduardo C. SolessioiD· 1 shared Frank A. MiddletoniD· 1 shared Sanaea Z. BhagwagariD· 1 shared Thuy La· 1 shared Xiaowen WangiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Arnav Rana

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 20, 2022

Mitochondrial protein import stress augments alpha-synuclein aggregation and neurodegeneration independent of bioenergetics

Liam P. Coyne, Arnav Rana, Xiaowen Wang…·Xin Jie Chen

This study shows that mitochondrial protein import stress increases alpha-synuclein aggregation and neurodegeneration without affecting bioenergetics in a Parkinson's disease mouse model.

4 citations

mouseexperimental assay

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GeneticsbioRxivPreprintNov 30, 2021

Mitochondrial DNA metabolism is coupled with 20S proteasome function via regulation of deoxyribonucleotide homeostasis in Saccharomyces cerevisiae

Xiaowen Wang, Arnav Rana, Liam P. Coyne…·Xin Jie Chen

The paper shows that 20S proteasome function regulates mtDNA stability in yeast by controlling dNTP homeostasis through Sml1 degradation.

DOI 10.1101/2021.11.30.470679

yeastexperimental assay

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