Insulin-independent glucose uptake in skeletal muscle by coupled SGLT and Na,K-ATPase transport
Natalie J. Norman, Tatiana L. Radzyukevich, Peter Chomczynski, Michal Rymaszewski, Izabela Fokt, Waldemar Priebe, Lucas Schmidt, Tiffany Zhu, Bryan Mackenzie, Julio Alberto Landero Figueroa, Judith A. Heiny
The paper identifies a novel insulin-independent glucose uptake pathway in skeletal muscle, termed mSGLT, which operates via SGLT and Na,K-ATPase and is active during exercise and adrenergic stimulation.
bioRxiv · Mar 27, 2026 · PreprintPhysiology