Rewired type I IFN signaling is linked to age-dependent differences in COVID-19
Lev Petrov, Sophia Brumhard, Sebastian Wisniewski, Philipp Georg, David Hillus, Anna Luisa Hiller, Rosario Astaburuaga-García, Nils Blüthgen, Emanuel Wyler, Katrin Vogt, Hannah-Philine Dey, Saskia Freifrau von Stillfried, Christina Iwert, Roman David Bülow, Bruno Märkl, , Birgit Sawitzki
This study identifies age-related rewiring of type I IFN signaling in immune cells linked to increased inflammation and altered antibody responses in COVID-19.
Cell Reports Medicine · Aug 1, 2025Peer-reviewedImmunology