Author

Rosario Astaburuaga-García

Humboldt-Universität zu BerlinORCID 0000-0003-1179-4080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Nils BlüthgeniD· 3 shared Alexandra TrinksiD· 1 shared Anja SieberiD· 1 shared Anna Luisa HilleriD· 1 shared Benjamin OndruschkaiD· 1 shared Bertram KlingeriD· 1 shared Birgit SawitzkiiD· 1 shared Bjoern PapkeiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

Nils BlüthgenORCID

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3 papers

Recent·Most cited

ImmunologyCell Reports MedicinePeer-reviewedAug 1, 2025

Rewired type I IFN signaling is linked to age-dependent differences in COVID-19

Lev Petrov, Sophia Brumhard, Sebastian Wisniewski…·Birgit Sawitzki

This study identifies age-related rewiring of type I IFN signaling in immune cells linked to increased inflammation and altered antibody responses in COVID-19.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyScience SignalingPeer-reviewedJul 22, 2025

Reporter-based screening identifies RAS-RAF stabilizing mutations as drivers of resistance to broad-spectrum RAS inhibition in colorectal cancer

Oleksandra Aust, Moritz R. T. Thiel, Eric Blanc…·Markus Morkel

5 citations

humanproteomics

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BioinformaticsBioinformaticsPeer-reviewedNov 1, 2024

RUCova: Removal of Unwanted Covariance in mass cytometry data

Rosario Astaburuaga-García, Thomas Sell, Samet Mutlu…·Nils Blüthgen

RUCova removes unwanted covariance in mass cytometry data using multivariate regression and PCA, preserving biological signals and improving analysis accuracy.

1 citation

statistical modeldimensionality reduction

𝕏 PostBluesky