Birgit Sawitzki

This study uses single-cell transcriptomics to show that SARS-CoV-2 variants reshape pediatric upper-airway immunity differently from adults.

This study identifies a cortical niche-specific macrophage subset that drives early osteoclastogenesis in bone healing through spatial immune-stromal interactions in young mice.

This study identifies distinct immune mechanisms in pancreatic inflammation during metabolic stress and aging using spatial and single-cell analyses.

This study identifies age-related rewiring of type I IFN signaling in immune cells linked to increased inflammation and altered antibody responses in COVID-19.

The paper investigates how aging and viral mutations affect pan-coronavirus immunity, finding reduced T cell responses in older individuals and mutation-driven impact on humoral immunity.