Roman David Bülow

Hypothermic and Normothermic Machine Perfusion Differentially Shape the Renal Cellular Landscape

This study compares hypothermic and normothermic machine perfusion in a murine kidney model, finding that NMP causes more severe tubular injury and immune cell mobilization compared to HMP.

A mixture of plant polyphenols unexpectedly aggravates liver metastasis of colorectal cancer in mice

This study shows that a plant polyphenol mixture accelerates liver metastasis in mice, suggesting potential immunomodulatory effects that require validation in immunocompetent models.

Hierarchical Phase-Contrast Tomography Imaging: Applicability in biomedical research

This paper demonstrates the application of Hierarchical Phase-Contrast Tomography (HiP-CT) in three biomedical case studies, revealing detailed organ structures at multiple scales.

Rewired type I IFN signaling is linked to age-dependent differences in COVID-19

This study identifies age-related rewiring of type I IFN signaling in immune cells linked to increased inflammation and altered antibody responses in COVID-19.

Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)

PILOT uses optimal transport to analyze single-cell and pathomics data, detecting disease-associated samples and non-linear changes in cell populations and tissue structures.