Author

Timothy James

Oxford University Hospitals NHS Trust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandro BarberisiD· 1 shared Alistair EastoniD· 1 shared Ashwin JainarayananiD· 1 shared Ashwin M. NandakumariD· 1 shared Avigail TayloriD· 1 shared Cameron R. Lang· 1 shared Clare L. VerrilliD· 1 shared Dimitrios DoultsinosiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alessandro BarberisORCID

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1 paper

Recent·Most cited

IGFs regulate cancer cell immune evasion in prostate cancer

Ashwin M. Nandakumar, Alessandro Barberis, Jin-Seon Kim, Cameron R. Lang, Jack V. Mills, Guillaume Rieunier, Dimitrios Doultsinos, Avigail Taylor, Ashwin Jainarayanan, Su Myat Phyu, Leticia Campo, Alistair Easton, Eileen E. Parkes, Timothy James, Freddie Charles Hamdy, , Valentine M. Macaulay

This study shows IGF-1 suppresses immune-related pathways in prostate cancer cells, reducing antigen presentation and increasing PD-L1, which may explain poor immunotherapy response.

Scientific Reports · Nov 3, 2025Peer-reviewedCancer Biology