Author
University of OxfordORCID 0000-0001-8148-5406Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Bruno Beernaert, Rose L. Jady‐Clark, Parin Shah…·Eileen E. Parkes
This study shows that chromosomal instability in esophageal adenocarcinoma drives an inflammatory tumor microenvironment through a cGAS-chemokine-myeloid axis, with CXCL8 as a key mediator.
Ashwin M. Nandakumar, Alessandro Barberis, Jin-Seon Kim…·Valentine M. Macaulay
This study shows IGF-1 suppresses immune-related pathways in prostate cancer cells, reducing antigen presentation and increasing PD-L1, which may explain poor immunotherapy response.
Joshua A. Bull, Eoghan J. Mulholland, Joshua W. Moore…·Simon John Leedham
The paper develops spatial descriptors using mathematical tools to analyze cell interactions in colorectal cancer progression and demonstrates their utility in identifying disease-related pathways.