Phospotyrosine proteomics reveals novel Zap70 and Itk pathway targets downstream of TCR and CAR in Jurkat T cells
Kenneth P. Callahan, Savannah S. Trychanh, Timothy Ro, Aisharja Mojumdar, Arthur R. Salomon
The paper evaluates the effects of Zap70 and Itk inhibitors on T cell activation and identifies novel phosphotyrosine targets using proteomics.
bioRxiv · Nov 3, 2025 · PreprintImmunology