Ryan Z Puterbaugh

This study introduces β-sheet breaking proline residues into FUS prion-like domain to prevent aggregation and toxicity while preserving phase separation and function.

This paper investigates how the disordered C-terminal domain of TDP-43 interacts with RNA and identifies key residues and structural features that mediate RNA recognition and binding specificity.

This study shows methionine oxidation in TDP-43's C-terminal domain disrupts structure and phase separation through region-specific mechanisms.

This study investigates the roles of TCPTP, PTPN22, and SHP1 in T cell phosphotyrosine regulation and TCR signaling using CRISPR/Cas9 and mass spectrometry, revealing distinct effects on pY levels and Erk1/2 feedback.

This study investigates how the inclusion of the ζ-chain affects phosphotyrosine signaling in CD19-CAR T cells using phosphoproteomics and inhibitor experiments.

The paper shows CLAMP, a DNA-binding factor, regulates sex-specific splicing by interacting with RNA and modulating RBP dynamics.