Author

Tiweng Chew

National University of Singapore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Boon Chuan LowiD· 2 shared Fumio MotegiiD· 2 shared Lester Bocheng Lin· 2 shared Olivia Xuan Liu· 2 shared Selwin K. WuiD· 1 shared Soumya Bunk· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Boon Chuan LowORCID

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2 papers

Recent·Most cited

A ZO-2 scaffolding mechanism regulates the Hippo signalling pathway.

Olivia Xuan Liu, Lester Bocheng Lin, Soumya Bunk, Tiweng Chew, Selwin K. Wu, Fumio Motegi, Boon Chuan Low

This study identifies ZO-2 as a scaffolding protein that regulates Hippo signaling by facilitating LATS1-mediated phosphorylation and inactivation of YAP.

FEBS Journal · Oct 27, 2024Peer-reviewedCell Biology

ZO-2 induces cytoplasmic retention of YAP by promoting a LATS1-ZO-2-YAP complex at tight junctions

Olivia Xuan Liu, Lester Bocheng Lin, Tiweng Chew, Fumio Motegi, Boon Chuan Low

The paper identifies ZO-2 as a scaffold that promotes LATS1-YAP complex formation at tight junctions, leading to YAP phosphorylation and cytoplasmic retention in response to cell density.

bioRxiv · Jun 25, 2018 · PreprintCell Biology