Boon Chuan Low

This study identifies fibrillar adhesions as the primary integrin complexes that respond to matrix topography, forming independently of focal adhesions.

This study shows that HIF-1α activation defines the SASP across different stressors, independent of micronuclei-induced cGAS/Sting activation.

This study identifies ZO-2 as a scaffolding protein that regulates Hippo signaling by facilitating LATS1-mediated phosphorylation and inactivation of YAP.

The paper identifies ZO-2 as a scaffold that promotes LATS1-YAP complex formation at tight junctions, leading to YAP phosphorylation and cytoplasmic retention in response to cell density.

This study identifies actomyosin contractility as a mechanism driving bile regurgitation in obstructive cholestasis by forming vesicles that relieve biliary pressure.