Author

Selwin K. Wu

Harvard UniversityORCID 0000-0002-5185-8467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Boon Chuan LowiD· 2 shared Celestine Z. Ho· 1 shared Dominic Zhuohong Chua· 1 shared Fieda O. Abderazzaq· 1 shared Fumio MotegiiD· 1 shared Lester Bocheng Lin· 1 shared Lin DengiD· 1 shared Nicole Flanagan· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Boon Chuan LowORCID

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2 papers

Recent·Most cited

The Senescence-Associated Secretory Phenotype constitutes HIF-1α activation but is independent of micronuclei-induced cGas/Sting activation

Celestine Z. Ho, Lin Deng, Remigio Picone, Fieda O. Abderazzaq, Nicole Flanagan, Dominic Zhuohong Chua, Boon Chuan Low, Selwin K. Wu

This study shows that HIF-1α activation defines the SASP across different stressors, independent of micronuclei-induced cGAS/Sting activation.

Molecular Biology of the Cell · Nov 26, 2025Peer-reviewedCell Biology

A ZO-2 scaffolding mechanism regulates the Hippo signalling pathway.

Olivia Xuan Liu, Lester Bocheng Lin, Soumya Bunk, Tiweng Chew, Selwin K. Wu, Fumio Motegi, Boon Chuan Low

This study identifies ZO-2 as a scaffolding protein that regulates Hippo signaling by facilitating LATS1-mediated phosphorylation and inactivation of YAP.

FEBS Journal · Oct 27, 2024Peer-reviewedCell Biology