An in vitro assay of MCTS1-DENR-dependent re-initiation and ribosome profiling uncover the activity of MCTS2 and distinct function of eIF2D
Romane Meurs, Mara De Matos, Adrian Bothe, Nicolas Guex, Tobias Weber, Aurelio A. Teleman, Nenad Ban, David Gatfield
The paper develops an in vitro re-initiation assay and uses ribosome profiling to show that MCTS2 and eIF2D have distinct roles in uORF-dependent translation.
bioRxiv · Jun 5, 2024 · PreprintMolecular Biology