Author

Adrian Bothe

ETH ZurichORCID 0009-0007-2710-1273Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Nenad BaniD· 2 shared Amisha Devan· 1 shared Andres V. ReyesiD· 1 shared Aurelio A. TelemaniD· 1 shared Carmen Jung· 1 shared David GatfieldiD· 1 shared Eric J. RossiD· 1 shared Hanna Suh· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Nenad BanORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 5, 2024

An in vitro assay of MCTS1-DENR-dependent re-initiation and ribosome profiling uncover the activity of MCTS2 and distinct function of eIF2D

Romane Meurs, Mara De Matos, Adrian Bothe…·David Gatfield

The paper develops an in vitro re-initiation assay and uses ribosome profiling to show that MCTS2 and eIF2D have distinct roles in uORF-dependent translation.

3 citations

humanproteomics

𝕏 PostBluesky

Cell BiologyMolecular CellPeer-reviewedApr 29, 2024

ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates

Jared F. Akers, Michael LaScola, Adrian Bothe…·Kamena K. Kostova

The paper identifies ZNF574 as a key factor in a quality control pathway that degrades defective ribosome intermediates in human cells.

13 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky