Opioid use disorder and brain health: observational andgenetic associations
Sara Javidnia, James M. Roe, Ville Karhunen, Dipender Gill, Steven Bell, Joseph D. Deak, Daniel F. Levey, Toinet Cronje, Stephen Burgess, Joel E. Gelernter, Klaus P. Ebmeier, Anya Topiwala
This paper investigates the causal impact of opioid use disorder on brain health outcomes using observational and genetic analyses, finding increased dementia risk associated with both OUD diagnoses and genetic predisposition to OUD.
medRxiv · Dec 18, 2024 · PreprintGenetic & Genomic Medicine