DIO3 coordinates photoreceptor development timing and fate stability in human retinal organoids
Christina McNerney, Clayton P. Santiago, Kiara C. Eldred, Ian A. Glass, Tom A. Reh, Arturo Hernández, Seth Blackshaw, Nathan D. Lord, Robert J. Johnston
This study identifies DIO3 as a regulator of photoreceptor development timing and fate stability in human retinal organoids, proposing an hourglass model for developmental progression.
Genes & Development · Jan 1, 2026Peer-reviewedDevelopmental Biology