Nathan D. Lord

This study identifies DIO3 as a regulator of photoreceptor development timing and fate stability in human retinal organoids, proposing an hourglass model for developmental progression.

SpaceTravLR identifies spatial functional microniches by modeling genetic perturbations across spatially resolved molecular networks, validated experimentally in a murine model.

This study develops optogenetic tools to control Nodal signaling patterns in zebrafish embryos, enabling precise spatial manipulation of signaling activity and rescue of developmental defects.

The paper shows that temporal BMP/Nodal signaling ratios drive tissue-specific convergence and extension movements during zebrafish gastrulation.

This study investigates how de novo proteins in yeast integrate into cellular systems using ancient targeting and degradation pathways, revealing a conserved molecular signature that enables their ER localization and regulation.

The paper shows that Nodal morphogen signaling patterns in zebrafish embryos are shaped by co-receptor Oep, which restricts ligand spread and sensitizes cells.