Author

Tomohiko Kawate

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Andrej ŠaliiD· 1 shared Ashley Y. Eng· 1 shared Deborah Tan HungiD· 1 shared James E. GomeziD· 1 shared Meghna GuptaiD· 1 shared Nitesh Kumar KhandelwaliD· 1 shared Robert Michael StroudiD· 1 shared Sree Ganesh BalasubramaniiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andrej ŠaliORCID

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1 paper

Recent·Most cited

Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporterefflux protein A

Nitesh Kumar Khandelwal, Meghna Gupta, James E. Gomez, Sulyman Barkho, Ziqiang Guan, Ashley Y. Eng, Tomohiko Kawate, Sree Ganesh Balasubramani, Andrej Šali, Deborah Tan Hung, Robert Michael Stroud

This study identifies two inhibitors of the Mtb efflux pump EfpA, determines their binding mechanisms, and suggests their potential for combination anti-tuberculosis therapy.

Nature Communications · Apr 1, 2025Peer-reviewedBiochemistry