Intranasal immunization with CPAF combined with cyclic-di-AMP induces a memory CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum
Taylor B. Poston, Jenna Girardi, Marie Kim, Peter Zwarycz, A Grace Polson, Kacy S. Yount, Courtne Hanlan, Ian Jaras Salas, Sarah Mae Lammert, Daisy Arroyo, Tony Bruno, Manhong Wu, James Rozzelle, Jeff Fairman, Aaron Palmer Esser-Kahn, Toni L. Darville
This study shows that intranasal immunization with CPAF and cyclic-di-AMP reduces bacterial burden in mice infected with Chlamydia muridarum by inducing memory CD4 T cell responses.
Vaccine · Nov 12, 2024Peer-reviewedImmunology