Mycoplasmal endosymbionts of Trichomonas vaginalis are associated with reduced risk for Chlamydia trachomatis endometrial infection in asymptomatic, coinfected, women.
Xuejun Sun, Kacy S. Yount, Nefer N Batsuli…·Catherine M. O’Connell
Author
University of North Carolina at Chapel HillORCID 0000-0003-1507-2202Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Xuejun Sun, Kacy S. Yount, Nefer N Batsuli…·Catherine M. O’Connell
Toni L. Darville, Jenna Girardi, Taylor B. Poston…·Xiaojing Zheng
This study uses Collaborative Cross mice to identify host genetic factors influencing Chlamydia muridarum infection outcomes, revealing distinct genetic pathways for bacterial burden and pathology.
Toni L. Darville, Xuejun Sun, Yu Zhang…·Xiaojing Zheng
The paper analyzes miRNA and mRNA expression in endometrial biopsies to show increased TGF-β pathways drive EMT and Treg differentiation in Chlamydia infection.
Sangmi Jeong, Tammy S. Tollison, Hayden N. Brochu…·Xinxia Peng
Taylor B. Poston, Jenna Girardi, Marie Kim…·Toni L. Darville
This study shows that intranasal immunization with CPAF and cyclic-di-AMP reduces bacterial burden in mice infected with Chlamydia muridarum by inducing memory CD4 T cell responses.
Wujuan Zhong, Toni L. Darville, Xiaojing Zheng…·Yun Li
This paper introduces a method to test mediation effects of multiple SNPs on various phenotypic outcomes, showing high power gains in simulations and real data applications.