Aaron Palmer Esser-Kahn

This study shows that β-glucan-induced trained immunity in mice enhances antibody levels after vaccination by improving antigen presentation and T-cell responses.

This study shows that intranasal immunization with CPAF and cyclic-di-AMP reduces bacterial burden in mice infected with Chlamydia muridarum by inducing memory CD4 T cell responses.

The paper identifies a small molecule, A1155463, that induces trained immunity in macrophages without being immunogenic, enhancing anti-tumor resistance in mice.