Cell BiologyGutPeer-reviewed
Tff2 marks gastric corpus progenitors that give rise to pyloric metaplasia/SPEM following injury
Ruhong Tu, Hua-Long Zheng, Biyun Zheng…·Timothy Cragin Wang
This study identifies Tff2+ progenitors in the gastric corpus as the primary source of SPEM and gastric cancer following injury, showing they can bypass metaplasia and progress directly to dysplasia.