GeneticsDisease Models & MechanismsPeer-reviewed
Activation of innate immune signalling during development predisposes to inflammatory intestine and shortened lifespan
Kyoko Yamashita, Ayano Oi, Hina Kosakamoto…·Fumiaki Obata
This study shows that early-life activation of the IMD immune pathway in Drosophila larvae leads to altered adult physiology, including shortened lifespan and changes in gut microbiota.
20 citations