Identification of repurposable cytoprotective drugs for Vanishing White Matter Disease
Neville S. Ng, Mauricio Castro Cabral-da-Silva, Simon Maksour, Tracey Berg, Martin Engel, Dina M. Silva, Dzung Do‐Ha, Jeremy Stephen Lum, Sonia Sanz Muñoz, Nadia Suarez-Bosche, Claire H. Stevens, Lezanne Ooi
This study identifies FDA-approved drugs that protect astrocytes in Vanishing White Matter Disease by targeting the integrated stress response and mitochondrial stress.
Translational Medicine Communications · Oct 21, 2020Peer-reviewedNeuroscience