FACT activity and histone H3-K56 acetylation promote optimal establishment of chromatin architecture independent of ongoing transcription in Saccharomyces cerevisiae
Laura L. McCullough, Trang H. Pham, Timothy J. Parnell, Mahesh B. Chandrasekharan, David J. Stillman, Tim Formosa
The paper investigates how FACT activity and H3-K56 acetylation influence chromatin architecture and transcription in yeast, finding they optimize transcription frequency and restore chromatin integrity independently of ongoing transcription.
bioRxiv · Aug 3, 2018 · PreprintGenomics