Author

Tristan Houghton

The University of Queensland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:rat· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Roger B. VarelaiD· 3 shared Susannah J. TyeiD· 3 shared Heather K. MacphersoniD· 2 shared Venea Dara DaygoniD· 2 shared Abbas Z. KouzaniiD· 1 shared Charles D. BlahaiD· 1 shared Isha ChawlaiD· 1 shared João QuevedoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Roger B. VarelaORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 6, 2025

Unpredictable circadian rhythm disruption in Wistar rats: biological and behavioural changes reflecting bipolar disorder pathophysiology

Heather K. Macpherson, Roger B. Varela, Sebastian McCullough…·Susannah J. Tye

This study investigates the effects of unpredictable circadian disruption on locomotor activity and molecular markers in rats, finding biphasic behavioral changes and altered inflammatory, stress, and metabolic profiles.

DOI 10.1101/2025.09.06.674601

ratbulk RNA-seq

𝕏 PostBluesky

NeuroscienceBipolar DisordersPeer-reviewedApr 1, 2024

Anti-manic effect of deep brain stimulation of the ventral tegmental area in an animal model of mania induced by methamphetamine

Roger B. Varela, Suelen Lucio Boschen, Nathanael James Yates…·Susannah J. Tye

This study investigates the anti-manic effects of VTA deep brain stimulation in a methamphetamine-induced mania model, showing both stimulation patterns reduce hyperlocomotion and modulate dopamine dynamics.

2 citations

ratexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 21, 2023

The role of IL-6 in dopamine dysregulation underlying anhedonia phenotype in rats

Roger B. Varela, Heather K. Macpherson, Tristan Houghton…·Susannah J. Tye

This study investigates how chronic ACTH treatment induces anhedonia-like behavior in rats by altering peripheral inflammation and central dopamine dynamics, with limited reversal by bupropion.

DOI 10.1101/2023.11.21.568169

ratproteomics

𝕏 PostBluesky