Molecular BiologyMolecular CellPeer-reviewed
Centromere inactivation during aging can be rescued in human cells
Sweta Sikder, Songjoon Baek, Truman Raleigh Mcneil, Yamini Dalal
This study shows that centromere inactivation during aging in human cells can be reversed by inhibiting p53 and LSD1/KDM1A, restoring centromeric proteins and transcripts.
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