Sweta Sikder

This study shows that KAT5 acetylates PC4 at K80 to enhance DNA repair, and this acetylation is critical for DNA damage response.

This study identifies T13F2.2 as a critical gene in C. elegans that affects chromatin structure, autophagy, and lifespan through RNAi depletion and transcriptomic analysis.

The paper investigates how an oncogenic lncRNA transgene affects epigenetic memory at a naive chromosomal locus, showing that epigenetic silencing can reverse ectopic CENP-A deposition over time.

This study shows that centromere inactivation during aging in human cells can be reversed by inhibiting p53 and LSD1/KDM1A, restoring centromeric proteins and transcripts.

This study shows that PC4 maintains genomic integrity by regulating chromatin structure and autophagy, with its loss increasing radiation resistance through autophagy enhancement.