Songjoon Baek

The paper defines a temporally resolved framework for GR-mediated gene regulation, identifying three binding classes and their functional links to transcriptional output.

The paper investigates how an oncogenic lncRNA transgene affects epigenetic memory at a naive chromosomal locus, showing that epigenetic silencing can reverse ectopic CENP-A deposition over time.

This study shows H1.5 interacts with CENP-A nucleosomes at centromeres, and its depletion causes centromere dysfunction and mitotic defects in human cells.

This study shows that centromere inactivation during aging in human cells can be reversed by inhibiting p53 and LSD1/KDM1A, restoring centromeric proteins and transcripts.

The paper develops a method to prioritize enhancers linked to pancreas disease risk by integrating chromatin interactions, machine learning, and single-cell perturbation assays.

The paper analyzes single-cell transcriptome and chromatin accessibility data to uncover transcription factor networks governing pancreatic endocrine cell lineage specification.