Deep Visual Proteomics links vascular smooth muscle cell phenotypes to atherosclerotic plaque stability
Elena Kratz, Ankit Sinha, Trusha Adeshara, Valentina Paloschi, Nadja Sachs, Jessica Pauli, Nadyia Glukha, Annalena Huber, Sara Schanda, Andreas Metousis, Tim Heymann, Daniela Branzan, Tore Bleckwehl, Sikander Hayat, Lars Mäegdefessel, Matthias Mann
This study uses Deep Visual Proteomics to analyze VSMC phenotypes in atherosclerotic plaques, finding spatially distinct phenotype distributions and a shift toward dedifferentiated states in unstable plaques.
bioRxiv · Jul 17, 2026 · PreprintSystems Biology