Pseudouridine selects RNAs for extracellular transport
Alessandro Scacchetti, Tuan D. Tran, Emily J. Shields, Lauren N. Reich, J. Kenneth Doherty, Julia A. Tasca, Grace E. Lee, Alejandro A. Vilcaes, Richard Lauman, Natalí L. Chanaday, Benjamin Aaron Garcia, Colin C. Conine, Roberto Bonasio
The paper identifies pseudouridine as a key modification enabling RNA extracellular transport and identifies MYL6 as a binding protein required for this process.
bioRxiv · Oct 28, 2025 · PreprintMolecular Biology