Alessandro Scacchetti

The paper identifies pseudouridine as a key modification enabling RNA extracellular transport and identifies MYL6 as a binding protein required for this process.

This study identifies the Tip60 acetylome as a marker of the proliferative state in Drosophila, revealing its role in cell cycle regulation through histone and non-histone acetylation.

The paper introduces LIDAR, a ligation-independent sequencing method that captures diverse RNA species, including tRNA-derived RNAs with blocked 3' termini, in mouse cells.

The paper identifies two DOMINO isoforms in Drosophila that form distinct complexes with different functions: DOM-B acts like SWR1 by depositing H2A.V, while DOM-A acts like NuA4 by acetylating H4K12.

This study shows that ACF1-containing chromatin remodeling complexes repress gene expression by maintaining a repressive chromatin state in Drosophila.