Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression
Giovanni Valenti, Pasquale Laise, Feijing Wu, Ryota Takahashi, Tuo Ruan, Alessandro Vasciaveo, Zhengyu Jiang, Hiroki Kobayashi, Masaki Sunagawa, Moritz A. Middelhoff, Henrik Nienhüser, Na Fu, Ermanno Malagola, Osmel Companioni, Yoku Hayakawa, , Timothy Cragin Wang
The paper identifies Dclk1-expressing cells in the pancreas and reveals their role in inhibiting pancreatic tumor progression through a tuft cell-ILC2 axis.
Cell Reports · May 22, 2025Peer-reviewedCancer Biology