Sleeve gastrectomy improves metabolic health, cognition, and Alzheimer's Disease pathology in 3xTG mice
Reji Babygirija, Julia A. Illiano, Michelle M. Sonsalla, Grace Zhu, Twinkle Mathew, Tristan Molkentin, Meredith Peterson, Carolyn Winder, Fan Xiao, Justin M. Wolter, Dudley W. Lamming, David A. Harris
This study shows that sleeve gastrectomy improves metabolic health, cognition, and Alzheimer's pathology in 3xTg-AD mice by modulating autophagy and insulin signaling.
bioRxiv · Apr 24, 2026 · PreprintNeuroscience