Snehal N. Chaudhari

This study shows that folic acid polyglutamylation activates MAP2K5 signaling to promote adipocyte lipid breakdown, revealing a novel role for folate in lipid homeostasis.

The paper shows that gut microbiota-derived folinic acid suppresses colorectal cancer progression by inhibiting calpain-2 and stabilizing E-cadherin.

This study shows that liver-specific SCD1 deficiency reduces hyperglycemia and hepatic steatosis in T1D through bile acid-FXR-Glut1 signaling, independent of insulin.

The paper identifies a gut microbial metabolite of methotrexate that alleviates gut inflammation by promoting mitochondrial STAT3 signaling.

This study shows that sleeve gastrectomy in lean mice improves metabolic health and protects against future obesity without weight loss.