BiochemistryStructurePeer-reviewed
Structural mechanism of HP1-dependent transcriptional repression and chromatin compaction
Vladyslava Sokolova, Jacob Miratsky, Vladimir V. Svetlov…·Dongyan Tan
This study determines the cryo-EM structure of HP1 bound to an H2A.Z nucleosome, revealing two binding sites and their roles in transcriptional repression and chromatin compaction.
13 citations