Author

Michael D. Brenowitz

Albert Einstein College of MedicineORCID 0000-0003-0048-1716Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Abhishek SingharoyiD· 1 shared Benjamin M. LortoniD· 1 shared Daniel GroomiD· 1 shared David ShechteriD· 1 shared Derek M. HuffmaniD· 1 shared Dongyan TaniD· 1 shared Evgeny NudleriD· 1 shared Evripidis GavathiotisiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Abhishek SingharoyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 29, 2026

The GNMT N-terminus Couples Folate Feedback to Methyl-donor Homeostasis

Isaac Kraz, Oi Wei Mak, Subray Hegde…·David Shechter

This study identifies the GNMT N-terminal tail and its phosphorylation at S9 as a regulatory mechanism linking folate feedback to SAM homeostasis.

DOI 10.64898/2026.05.26.727678

mouseproteomics

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BiochemistryStructurePeer-reviewedOct 8, 2024

Structural mechanism of HP1-dependent transcriptional repression and chromatin compaction

Vladyslava Sokolova, Jacob Miratsky, Vladimir V. Svetlov…·Dongyan Tan

This study determines the cryo-EM structure of HP1 bound to an H2A.Z nucleosome, revealing two binding sites and their roles in transcriptional repression and chromatin compaction.

13 citations

humanstructural biology

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