Author

Tyzoon K. Nomanbhoy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

John W. Kozarich· 2 shared Alexandria H. Berry· 1 shared Ashish Radadiya· 1 shared Bei Li· 1 shared Brian E. Nordin· 1 shared Christopher A. Amantea· 1 shared Claudine Bisson· 1 shared David W. Rice· 1 shared

Activity by Year

2016-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

John W. Kozarich

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 29, 2018

Molecular basis of human asparagine synthetase inhibitor specificity

Wen Zhu, Ashish Radadiya, Claudine Bisson…·Nigel G. J. Richards

The paper determines the X-ray crystal structure of human ASNS and builds a computational model of the enzyme-inhibitor complex to understand specificity.

DOI 10.1101/428508

humanstructural biology

𝕏 PostBluesky

ImmunologybioRxivJul 26, 2016

Reinvestigating the role of ERK5: kinase activity is not required for cellular immune response or proliferation

Emme C.K. Lin, Christopher A. Amantea, Tyzoon K. Nomanbhoy…·Jonathan S. Rosenblum

This study identifies that ERK5 kinase inhibitors lack anti-inflammatory and anti-proliferative effects, suggesting previously observed effects are due to off-target bromodomain inhibition.

DOI 10.1073/pnas.1609019113

experimental assaydrug response / drug discovery

𝕏 PostBluesky