Author

John W. Kozarich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Tyzoon K. Nomanbhoy· 2 shared Alexandria H. Berry· 1 shared Ashish Radadiya· 1 shared Bei Li· 1 shared Brian E. Nordin· 1 shared Christopher A. Amantea· 1 shared Claudine Bisson· 1 shared David W. Rice· 1 shared

Activity by Year

2016-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Tyzoon K. Nomanbhoy

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2 papers

Recent·Most cited

Molecular basis of human asparagine synthetase inhibitor specificity

Wen Zhu, Ashish Radadiya, Claudine Bisson, Brian E. Nordin, Patrick Baumann, Tsuyoshi Imasaki, Sabine A. Wenzel, Svetlana E. Sedelnikova, Alexandria H. Berry, Tyzoon K. Nomanbhoy, John W. Kozarich, Yi Jin, Yuichiro Takagi, David W. Rice, Nigel G. J. Richards

The paper determines the X-ray crystal structure of human ASNS and builds a computational model of the enzyme-inhibitor complex to understand specificity.

bioRxiv · Sep 29, 2018 · PreprintBiochemistry

Reinvestigating the role of ERK5: kinase activity is not required for cellular immune response or proliferation

Emme C.K. Lin, Christopher A. Amantea, Tyzoon K. Nomanbhoy, Helge Weissig, Junichi Ishiyama, Yi Hu, Shyama Sidique, Bei Li, John W. Kozarich, Jonathan S. Rosenblum

This study identifies that ERK5 kinase inhibitors lack anti-inflammatory and anti-proliferative effects, suggesting previously observed effects are due to off-target bromodomain inhibition.

bioRxiv · Jul 26, 2016Immunology