Author

U. Hansen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

H. G. Chin· 2 shared S. E. Schaus· 2 shared A. Ludwig· 1 shared A. Moeller-Kerutt· 1 shared A.-C. Groh· 1 shared C. Reinhard· 1 shared C. Ruse· 1 shared C. S. Pedamallu· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

H. G. Chin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Runaway resorption of microcracks contributes to age-related hip-fracture patients

M. Gray, O. Boughton, C. Wiles, C. Reinhard, N. T. Vo, R. Atwood, R. Stavri, J. Cobb, U. Hansen, R. Abel

The paper investigates microdefects in hip-fracture patients and finds they are more prevalent and negatively correlate with bone strength.

bioRxiv · Jun 9, 2024Bioengineering

PALS1 is a key regulator of the lateral distribution of tight junction proteins in renal epithelial cells.

A.-C. Groh, S. Kleimann, P. Nedvestky, M. Behrens, A. Moeller-Kerutt, V. Hoeffken, S. Ghosh, U. Hansen, M. P. Krahn, A. Ludwig, K. Ebnet, H. Pavenstaedt, T. Weide

This study shows that PALS1 regulates tight junction protein localization at bicellular junctions in renal epithelial cells, preventing increased paracellular permeability.

bioRxiv · Apr 27, 2023Cell Biology

Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI.

U. Hansen, D. F. Holmes, P. Bruchner, P. Bishop

bioRxiv · Jun 2, 2020Biochemistry

Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence

J. L. S. Willoughby, K. George, M. P. Roberto, H. G. Chin, P. Stoiber, H. Shin, C. S. Pedamallu, S. E. Schaus, K. Fitzgerald, J. Shah, U. Hansen

This study shows that inhibiting LSF with FQI1 or siRNA causes mitotic delays and cell death in HeLa cells, supporting LSF as a cancer therapeutic target.

bioRxiv · Jan 26, 2020Cancer Biology

Transcription factor LSF facilitiates lysine methylation of α-tubulin by microtubule-associated SET8

H. G. Chin, P. O. Esteve, C. Ruse, J. Lee, S. E. Schaus, S. Pradhan, U. Hansen

The paper identifies LSF as a facilitator of SET8-mediated α-tubulin methylation, revealing a novel role for these proteins in cytoskeletal modification during mitosis.

bioRxiv · Jun 10, 2019Biochemistry