S. Pradhan

Effects of Exercise Frequency on Aortic Calcification in Hyperlipidemic Mice

This study examines the effect of exercise frequency on aortic calcification in hyperlipidemic mice, finding that 5 days/week low-speed treadmill exercise reduces 18F-NaF uptake and cardiac remodeling.

Viral attachment blocking chimera composed of DNAorigami and nanobody inhibits Pseudorabies Virusinfection in vitro

This paper develops a Viral Attachment Blocking Chimera (VirABloC) using DNA origami and nanobodies to inhibit Pseudorabies Virus infection in vitro, achieving a low IC50.

Comparative Radiopathology of Male Reproductive Organs in Sprague Dawley Rats Administered with Curcuma longa and Ocimum sanctum Against Acute Gamma Irradiation

This study evaluates the radioprotective effects of Curcuma longa and Ocimum sanctum on male reproductive organs of rats exposed to acute gamma irradiation, finding that their combination provides better protection than either alone.

Differential scanning fluorimetry as a measure of functionality of refolded anti-malarial antibody fragments

This study uses differential scanning fluorimetry to assess the functionality of refolded anti-malarial antibody fragments, finding that 4B7-Db retains activity while 1245-Db shows weak recognition.

Newcastle disease burden in Nepal and efficacy of Tablet I-2 vaccine in commercial and backyard poultry production

The paper assesses Newcastle Disease burden in Nepal and evaluates the efficacy of the I-2 vaccine in poultry, finding high sero-prevalence and identifying new NDV strains, with the vaccine showing over 85% efficacy.

A general, highly efficient and facile synthesis of biocompatible rhodamine dyes and probes for live-cell multicolor nanoscopy

This paper develops a new synthesis method for rhodamine dyes that enables efficient, scalable production of biocompatible fluorescent probes for live-cell imaging.

In vitro reconstitution demonstrates the amyloid-beta mediated myelin membrane deformation

This study shows A{beta}-40 induces myelin membrane tubulation in vitro through binding and aggregation, revealing mechanisms of potential neuronal demyelination in Alzheimer's Disease.

A high throughput lipidomics method using scheduled multiple reaction monitoring

This paper introduces a high-throughput lipidomics method using scheduled multiple reaction monitoring to detect over 1000 lipid species, including structural isomers, and identifies changes in lipid composition due to Vitamin B12 deficiency.

Transcription factor LSF facilitiates lysine methylation of α-tubulin by microtubule-associated SET8

The paper identifies LSF as a facilitator of SET8-mediated α-tubulin methylation, revealing a novel role for these proteins in cytoskeletal modification during mitosis.

Mechanochemical feedback and control of endocytosis and membrane tension

The paper identifies a negative feedback loop between membrane tension and the CLIC/GEEC pathway mediated by vinculin and GBF1.