Author

U. S. Srinivas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D. Jeyasekharan· 1 shared A. Shendre· 1 shared B. W. Q. Tan· 1 shared C. Frezza· 1 shared D. Kappei· 1 shared D. S. P. Tan· 1 shared G. K. Ramachandran· 1 shared H. Yang· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. D. Jeyasekharan

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1 paper

Recent·Most cited

PLK1 inhibition selectively kills ARID1A deficient cells through uncoupling of oxygen consumption from ATP production

U. S. Srinivas, G. K. Ramachandran, J. D. Wardyn, M. M. Hoppe, Y. Peng, S. Lim, M. Y. Lee, P. C. Peethala, O. An, A. Shendre, B. W. Q. Tan, T. S. C. Norbert, P. Jaynes, L. Hu, R. Jakhar, , A. D. Jeyasekharan

This study identifies ARID1A deficiency as a biomarker for PLK1 inhibitor sensitivity by revealing a mitochondrial metabolic vulnerability in these cells.

bioRxiv · Jun 1, 2021 · PreprintCancer Biology