Evolutionary potential of the Escherichia coli antimutator ΔnudJ is reduced via altered mutational spectrum
Rowan Green, Huw Richards, Deniz Ozbilek, Francesca Tyrrell, V Barton, Simon C. Lovell, Danna R. Gifford, Mato Lagator, Andrew J. McBain, Rok Krašovec, Knight Cg
This study examines how the antimutator ΔnudJ in Escherichia coli reduces mutation rate and alters mutational spectrum, leading to decreased antibiotic resistance potential.
bioRxiv · Jan 28, 2025 · PreprintEvolutionary Biology