Author

V. Alcazer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

C. Caux· 2 shared L. Moudombi· 2 shared M. Ardin· 2 shared M. Hubert· 2 shared M.-C. Michallet· 2 shared A. Cerwenka· 1 shared A. Eberhardt· 1 shared A. Imanci· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

C. Caux

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting Heterochromatin Eliminates Malignant Stem Cells in Chronic Myelomonocytic Leukemia Through Reactivation of Retroelements and Innate Immune pathways

D. Hidaoui, A. Porquet, R. Chelbi, M. Bohm, A. Polizou, V. Alcazer, S. Depil, A. Imanci, M. Morabito, A. Renneville, D. Selimoglu-Buet, S. Thepot, R. Itzykson, L. Laplane, N. Droin, , F. PORTEU

This study shows that combining DNA hypomethylating agents with H3K9me2 inhibitors reactivates immune pathways and eliminates malignant stem cells in CMML by targeting heterochromatin disorganization.

bioRxiv · Feb 2, 2024Cancer Biology

A Unique Polyfunctional IL-33-responsive ST2⁺ NK cell State Potentiates Antitumor Immunity and Response to Immunotherapy

A. Eberhardt, E. Blanc, V. Picant, A. Voissiere, L. Revol-Bauz, T. Casini, V. Alcazer, D. Poujol, L. Tonon, R. Schneider, E. Picard, Y. Rocca, M. Ardin, F. Onodi, C. Degletagne, , N. Bendriss-Vermare

The paper identifies a unique ST2+ NK cell state that enhances antitumor immunity and response to immunotherapy through IL-33 and IL-12 signaling.

bioRxiv · Feb 14, 2023 · PreprintCancer Biology

Gene signature of circulating platelet-bound neutrophils is associated with poor prognosis in cancer patients

P. Lecot, M. Ardin, S. Dussurgey, V. Alcazer, L. Moudombi, M. Hubert, A. Swalduz, H. Hernandez-Vargas, A. Viari, C. Caux, M.-C. Michallet

The paper identifies a gene signature in neutrophil-platelet aggregates (NPAs) associated with poor prognosis in cancer patients.

bioRxiv · Aug 26, 2021Immunology