Author

M.-C. Michallet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

C. Caux· 4 shared M. Ardin· 4 shared L. Moudombi· 3 shared M. Hubert· 3 shared A. Puisieux· 2 shared A. Voissiere· 2 shared C. Degletagne· 2 shared D. Poujol· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersCancer Biology

C. Caux

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Spatial transcriptomics reveal pitfalls and opportunities for the detection of rare high-plasticity breast cancer subtypes

A. Coutant, V. Cockenpot, L. Muller, C. Degletagne, R. Pommier, L. Tonon, M. Ardin, M.-C. Michallet, C. Caux, M. Laurent, A.-P. Morel, P. Saintigny, A. Puisieux, M. Ouzounova, P. Martinez

The paper uses spatial transcriptomics to identify specific markers for rare high-plasticity breast cancer subtypes, showing that bulk expression signatures are limited by stromal contamination.

bioRxiv · Apr 24, 2023Cancer Biology

CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

A. Sanlaville, A. Voissiere, D. Poujol, M. Hubert, S. Andre, C. Perret, J.-P. Foy, N. Goutagny, M. Malfroy, I. Durand, M. Chalons, J. Valladeau-Guilemond, P. Saintigny, A. Puisieux, C. Caux, , N. Bendriss-Vermare

The paper shows CD4 T cells and neutrophils promote EMT in breast cancer by analyzing murine tumor models and human cohorts.

bioRxiv · Feb 15, 2023 · PreprintCancer Biology

A Unique Polyfunctional IL-33-responsive ST2⁺ NK cell State Potentiates Antitumor Immunity and Response to Immunotherapy

A. Eberhardt, E. Blanc, V. Picant, A. Voissiere, L. Revol-Bauz, T. Casini, V. Alcazer, D. Poujol, L. Tonon, R. Schneider, E. Picard, Y. Rocca, M. Ardin, F. Onodi, C. Degletagne, , N. Bendriss-Vermare

The paper identifies a unique ST2+ NK cell state that enhances antitumor immunity and response to immunotherapy through IL-33 and IL-12 signaling.

bioRxiv · Feb 14, 2023 · PreprintCancer Biology

Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses

L. Mangiante, N. Alcala, A. Di Genova, A. Sexton-Oates, A. Gonzalez-Perez, A. Khandekar, E. Bergstrom, J. Kim, C. Giacobi, N. Le-Stang, S. Boyault, C. Cuenin, S. Tabone-Eglinger, F. Damiola, C. Voegele, , Meyer

This study identifies four sources of heterogeneity in MPM using multi-omic factor analysis, showing how genomic events shape molecular profiles and clinical behavior.

bioRxiv · Sep 27, 2021Cancer Biology

Gene signature of circulating platelet-bound neutrophils is associated with poor prognosis in cancer patients

P. Lecot, M. Ardin, S. Dussurgey, V. Alcazer, L. Moudombi, M. Hubert, A. Swalduz, H. Hernandez-Vargas, A. Viari, C. Caux, M.-C. Michallet

The paper identifies a gene signature in neutrophil-platelet aggregates (NPAs) associated with poor prognosis in cancer patients.

bioRxiv · Aug 26, 2021Immunology

A ganglioside-based senescence-associated immune checkpoint

C. Iltis, L. Seguin, L. Cervera, L. Duret, T. Hamidouch, S. Kunz, O. Croce, C. Delannoy, Y. Guerardel, F. Allain, L. Moudombi, P. Hofman, E. Cosson, J. Guglielmi, T. Pourcher, , J. Cherfils-Vicini

This paper identifies GD3 as a senescence-associated immune checkpoint that suppresses NK cell-mediated clearance of senescent cells, showing that targeting GD3 can enhance anti-fibrotic effects in a mouse model.

bioRxiv · Apr 23, 2021 · PreprintImmunology