Author

V. Allain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

A. G. Rothrock· 2 shared J. Eyquem· 2 shared A. J. Millan· 1 shared A. Shemesh· 1 shared B. J. Sytsma· 1 shared F. Faizee· 1 shared F. L. Pan· 1 shared G. Ureno· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

A. G. Rothrock

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Author profile →

2 papers

Recent·Most cited

Spleen Tyrosine Kinase (SYK) negatively regulates ITAM-mediated human NK cell signaling and CD19-CAR NK cell efficacy

A. J. Millan, V. Allain, I. Nayak, O. A. Aguilar, J. S. Arakawa- Hoyt, G. Ureno, A. G. Rothrock, A. Shemesh, J. Eyquem, J. Das, L. L. Lanier

This study shows that SYK negatively regulates NK cell signaling and that its deletion enhances CD19-CAR NK cell efficacy in cancer immunotherapy.

bioRxiv · Jul 9, 2024 · PreprintImmunology

Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells

B. J. Sytsma, V. Allain, S. Bourke, F. Faizee, M. Fathi, R. Berdeaux, L. M. R. Ferreira, J. W. Brewer, L. Li, F. L. Pan, A. G. Rothrock, W. A. Nyberg, Z. Li, L. H. Wilson, J. Eyquem, R. S. Pawell

This study introduces hydroporation as a scalable and efficient method for delivering CAR-T cells, achieving higher yields and viability compared to traditional methods.

bioRxiv · Jun 25, 2024Bioengineering