Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
S. S. Armstrong, D. G. Chen, S. Kumar, J. R. Heath, M. Feinstein, J. R. Greenland, D. R. Calabrese, L. L. Lanier, K. Ley, A. Shemesh
The paper uses CITE-seq to analyze NK cell alterations in CAD patients, finding SPON2/IFNG ratio and adaptive NK cell signatures correlate with disease severity and inflammation.
bioRxiv · Mar 22, 2024 · PreprintImmunology
J. Yang, L. Wang, J. R. Byrnes, L. L. Kirkemo, H. Driks, C. Belair, O. A. Aguilar, L. L. Lanier, J. A. Wells, L. Fong, R. Blelloch
This study shows PVRL2 suppresses anti-tumor immunity independently of PVRIG and TIGIT, with deletion reducing tumor growth more than PD-L1 loss.
bioRxiv · Jan 26, 2024 · PreprintImmunology
D. Wethington, S. Ahmad, M. Potempa, G. Giuliani, O. A. Aguilar, M. Poudel, S. Grassmann, W. Stewart, N. M. Adams, J. C. Sun, L. L. Lanier, J. Das
This study quantifies how clonal stochasticity in NK cell responses to MCMV arises from proliferation and death dynamics of mature NK subsets.
bioRxiv · Sep 7, 2023Immunology
R. Saigusa, J. Vallejo, R. Gulati, S. S. A. Suthahar, V. Suryawanshi, A. Alimadadi, J. Makings, C. P. Durant, A. Freuchet, P. Roy, Y. Ghosheh, W. Pandori, T. Pattarabanjird, F. Drago, C. A. McNamara, , K. Ley
The paper uses scRNA-Seq and CITE-Seq to analyze CD4+ T cells from patients with and without coronary artery disease and diabetes, identifying sex-specific differences and gene expression patterns.
bioRxiv · May 16, 2022Immunology
A. Shemesh, D. R. Calabrese, J. Arakawa-Hoyt, J. R. Greenland, L. L. Lanier
The paper shows that NK cell division and mTOR activity regulate FcRγ expression, with rapamycin and TGFβ reducing FcRγ levels by suppressing division.
bioRxiv · Aug 3, 2021Immunology
J. Vallejo, R. Saigusa, R. Gulati, Y. Ghosheh, C. P. Durant, P. Roy, E. Ehinger, T. Pattarabanjird, L. E. Padgett, C. E. Olingy, D. B. Hanna, A. L. Landay, R. P. Tracy, J. M. Lazar, W. J. Mack, , K. Ley
The paper develops combined protein and transcript single-cell RNA sequencing in PBMCs, identifying more cell subsets than traditional methods and showing disease-related transcriptome differences in HIV patients.
bioRxiv · Sep 10, 2020Immunology
Y. Su, D. Chen, C. Lausted, D. Yuan, J. Choi, C. Dai, V. Voillet, K. Scherler, P. Troisch, V. R. Duvvuri, P. Baloni, G. Qin, B. Smith, S. Kornilov, C. Rostomily, , the
This study integrates multi-omic data from COVID-19 patients to identify immune response patterns linked to disease severity.
bioRxiv · Jul 27, 2020 · PreprintImmunology
J. L. McKechnie, D. Beltran, A. Pitti, L. Saenz, A. B. Arauz, R. Vergara, E. Harris, L. L. Lanier, C. A. Blish, S. Lopez-Verges
This study shows that HLA class I upregulation during dengue virus infection suppresses natural killer cell activity, potentially contributing to disease progression.
bioRxiv · Jul 11, 2019Immunology
N. W. Zammit, O. M. Siggs, P. Gray, K. Horikawa, S. R. Daley, D. B. Langley, D. Cultrone, E. K. Malle, S. N. Walters, J. E. Villanueva, J. Warren, A. Russell, M. J. Cowley, V. Gayevskiy, M. E. Dinger, , M. E. Craig
The paper identifies TNFAIP3 variants in humans, Denisovans, and mice that modulate A20 phosphorylation, revealing a genetic mechanism for balancing immunity and microbial tolerance.
bioRxiv · Mar 27, 2019 · PreprintImmunology